Table 3 ROC analysis of plasma and urinary cytokines (controls versus knee OA)
| Â | pCXCL16 | pIL-15 | uCCL2 | uCCL11 |
|---|---|---|---|---|
AUC | 0.81 | 0.76 | 0.97 | 0.99 |
95% CI | 0.66–0.96 | 0.59–0.92 | 0.92–1.00 | 0.96–1.00 |
P-value | 0.006** | 0.03* | 0.0002*** | 0.0001*** |
Cut-off (pg/ml) | 1241 | 3.8 | 1.1 | 0.5 |
Sensitivity | 0.57 | 0.61 | 0.91 | 0.92 |
Specificity | 1.00 | 1.00 | 1.00 | 1.00 |
| Â | uCCL19 | uCXCL16 | uIL-8 | uIL-12p70 |
|---|---|---|---|---|
AUC | 0.88 | 0.97 | 0.83 | 0.90 |
95% CI | 0.68–1.00 | 0.91–1.00 | 0.58–1.00 | 0.79–1.00 |
P-value | 0.026* | 0.0002*** | 0.002** | 0.002** |
Cut-off (pg/ml) | 0.1 | 0.2 | 0.06 | 1.6 |
Sensitivity | 0.78 | 0.84 | 0.90 | 0.78 |
Specificity | 1.00 | 1.00 | 0.75 | 1.00 |