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Table 2 Comparison of demographic data and serum and synovial fluid analysis between septic and nonseptic inflammatory arthritis**

From: Tryptophanyl tRNA synthetase is an alternative synovial biomarker for diagnosis of septic arthritis in knee joint

 

Septic arthritis group (n = 9)

Nonseptic arthritis group (n = 53)

P value

Mean

(Standard deviation)

Mean

(Standard deviation)

Age (years)

72.67

(16.01)

68.87

(15.42)

0.522

Sex, Male [% (M:F)]

44.4% (4:5)

43.4% (23:30)

1.000*

Comorbidity, diabetes

33.3% (3/9)

22.6% (12/53)

0.434*

Body temperature (°C)

37.03

(0.47)

37.40

(1.03)

0.488

Blood tests

 Hb

10.73

(1.40)

11.31

(2.24)

0.392

 WBC

13.70

(3.87)

9.85

(3.96)

0.029

 Platelets

181.29

(46.72)

260.67

(100.12)

0.049

Diff. count of segmental neutrophils (%)

85.16

(8.90)

71.55

(11.86)

0.006

 ESR

52.00

 

39.20

(33.24)

0.743

 CRP

20.60

(5.70)

9.50

(6.99)

 < 0.001

 Uric acid

4.43

(0.67)

5.33

(2.04)

0.243

 Rheumatoid factor

  

7.25

(2.19)

 

 Anti-CCP Aba

  

5.60

  

 PT

12.30

 

11.42

(1.71)

0.652

 PT sec

20.70

(9.76)

12.90

(2.02)

0.460

 INR

1.60

(0.74)

1.12

(0.15)

0.384

 PT percent

50.55

(31.47)

84.27

(19.68)

0.360

Synovial analysis

 Specific gravity

1.02

(0.01)

1.02

(0.01)

0.420

 PH

7.75

(0.46)

7.81

(0.53)

0.740

 RBC

13119.67

(4466.31)

8939.19

(18730.52)

0.282

 WBC

142,778.00

(116,744.85)

48,351.46

(34,370.59)

0.024

Synovial biomarkers

 WRS (ng/mL)

773.43

(513.51)

159.17

(191.99)

0.012

 α-defensin (ng/mL)

282.11

(71.69)

186.05

(132.83)

0.013

 CRPb

830.74

(209.88)

900.20

(113.60)

0.359

  1. Value of P < 0.05 are displayed in bold
  2. *Dichotomous variables are presented as ratios (percentage), and continuous data are presented as mean and standard deviation. The Wilcoxon rank sum test or Fisher’s test (septic arthritis versus nonseptic arthritis) were used when appropriate
  3. aCCP Ab Cyclic citrullinated peptide antibody
  4. bCRP C-reactive protein