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Table 3 Optimal diagnostic thresholds and their sensitivities, specificities, and predictive values for predicting joint infection

From: Tryptophanyl tRNA synthetase is an alternative synovial biomarker for diagnosis of septic arthritis in knee joint

Test

Optimal diagnostic threshold

Sensitivity (%)

Specificity (%)

Positive predictive value (%)

Negative predictive value (%)

Area under receiver operating characteristic curve (%)

P value for area under curve

Serum CRP (mg/L)

18.210

77.7

49.1

20.5

92.8

86.5

0.010

Synovial fluid

 WBC count (/µL)

81.120

77.7

92.4

63.6

96.0

91.7

0.003

 WRS (ng/mL)

417.9

88.9

88.7

57.1

88.7

88.5

0.008

 α-defensin (ng/mL)

300.8

88.9

86.8

53.3

97.8

82.3

0.022

 CRP

950.0

55.5

54.7

17.2

87.8

54.7

0.740

  1. Boldface text indicates statistical significance
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Knee Surgery & Related Research

ISSN: 2234-2451